Analysis of micronutrient nutritional deficiency in Covid-19 deaths among non-reserved indigenous people in Campo Grande
DOI:
https://doi.org/10.18593/evid.34450Keywords:
Epidemiological Surveillance Services, Hypovitaminosis, Iron, Vitamin D, ZincAbstract
The deficiency of Vitamin D, Zinc, and Iron can exacerbate the effects of COVID-19; studying its occurrence in deaths improves diagnosis and health interventions. This study describes the occurrence of Vitamin D, Zinc, and Iron deficiencies in COVID-19 deaths in the state of Mato Grosso do Sul, in the municipality of Campo Grande, during the period from 2020 to 2021. Clinical-laboratory and epidemiological records positive for COVID-19 by RT-PCR, with signs and symptoms starting during the period, and controls with multivariate analysis were used. A total of 75 cases were identified; the age group with 57.3% of the cases was from 35 to 44 years old, and the most frequent signs and symptoms were headache and oxygen saturation ≤ 95%, with a frequency of 86.6%. The length of hospital stays of 15 days or more showed a strong association with deaths. Given the analysis of the nutritional deficiency of Vitamin D, Zinc, and Iron in non-resident indigenous patients with COVID-19 deaths in Campo Grande, Mato Grosso do Sul, the importance of interventions for the health promotion of this population is highlighted.
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Ângelo, K. H. de A., Silva Filho, P. F. da, Araújo, N. D. de, Guedes, T. A. L., & Almeida, L. H. A. de. (2021). Suplementação nutricional como abordagem terapêutica no transtorno do espectro autista: Uma revisão de literatura. Research, Society and Development, 10(9), e1610917745. https://doi.org/10.33448/rsd-v10i9.17745
Aziz, J., Rahman, M. T., & Vaithilingam, R. D. (2021). Dysregulation of metallothionein and zinc aggravates periodontal diseases. Journal of Trace Elements in Medicine and Biology: Organ of the Society for Minerals and Trace Elements (GMS), 66, 126754. https://doi.org/10.1016/j.jtemb.2021.126754
Ben Abdallah, S., Mhalla, Y., Trabelsi, I., Sekma, A., Youssef, R., Bel Haj Ali, K., Ben Soltane, H., Yacoubi, H., Msolli, M. A., Stambouli, N., Beltaief, K., Grissa, M. H., Khrouf, M., Mezgar, Z., Loussaief, C., Bouida, W., Razgallah, R., Hezbri, K., Belguith, A., & Belkacem, N. (2022). Twice-Daily Oral Zinc in the Treatment of Patients With Coronavirus Disease 2019: A Randomized Double-Blind Controlled Trial. Clinical Infectious Diseases, 76(2), 185–191. https://doi.org/10.1093/cid/ciac807
Brighenti, S., Bergman, P., & Martineau, A. R. (2018). Vitamin D and tuberculosis: where next? Journal of Internal Medicine, 284(2), 145–162. https://doi.org/10.1111/joim.12777
Chandra, R. K. (1992). Protein-Energy Malnutrition and Immunological Responses. The Journal of Nutrition, 122(suppl_3), 597–600. https://doi.org/10.1093/jn/122.suppl_3.597
FAO, FIDA, OPS, WFP, & UNICEF. (2023). Panorama regional de la seguridad alimentaria y nutricional – América Latina y el Caribe 2022. In openknowledge.fao.org. FAO; FIDA; OPS; PMA; UNICEF; https://openknowledge.fao.org/handle/20.500.14283/cc3859es
Gibbons, J. B., Norton, E. C., McCullough, J. S., Meltzer, D. O., Lavigne, J., Fiedler, V. C., & Gibbons, R. D. (2022). Association between vitamin D supplementation and COVID-19 infection and mortality. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-24053-4
Ghelani, D., Alesi, S., & Mousa, A. (2021). Vitamin D and COVID-19: An Overview of Recent Evidence. International Journal of Molecular Sciences, 22(19), 10559. https://doi.org/10.3390/ijms221910559
Gombart, A. F., Pierre, A., & Maggini, S. (2020). A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection. Nutrients, 12(1). https://doi.org/10.3390/nu12010236
Hernandes, L. E. C. O. (2024). Atenção à saúde dos povos indígenas em contextos urbanos. 2024. https://www.anpr.org.br/artigos/atencao-a-saude-dos-povos-indigenas-em-contextos-urbanos
Hébert, J. R. (2022, January 1). Chapter 2 – History of nutrition and inflammation. In J. R. Hébert & L. J. Hofseth (Eds.), Diet, Inflammation, and Health. Academic Press. https://www.sciencedirect.com/science/article/pii/B978012822130300003X
Leite, M. S., Ferreira, A. A., Bresan, D., Araujo, J. R., Tavares, I. do N., & Santos, R. V. (2020). Indigenous protagonism in the context of food insecurity in times of Covid-19. Revista de Nutrição, 33. https://doi.org/10.1590/1678-9865202033e200171
Lima, A. L. L. de, Silva, A. C. F. da, Konno, S. C., Conde, W. L., Benicio, M. H. D., & Monteiro, C. A. (2010). Causas do declínio acelerado da desnutrição infantil no Nordeste do Brasil (1986-1996-2006). Revista de Saúde Pública, 44(1), 17–27. https://doi.org/10.1590/S0034-89102010000100002
Mancilha, E. M. B., & Oliveira, J. S. R. de. (2021). SARS-CoV-2 association with hemoglobin and iron metabolism. Revista da Associação Médica Brasileira, 67(9), 1349–1352. https://doi.org/10.1590/1806-9282.20210555
Meller, F. de O., Santos, L. P. dos, Vargas, B. L., Quadra, M. R., Martins, C. D., & Schäfer, A. A. (2023). Household food insecurity before and during COVID-19 pandemic and its association with perceived stress: population-based studies. Cadernos de Saúde Pública, 39(1). https://doi.org/10.1590/0102-311xen285121
Mendes, A. M., Bastos, J. L., Bresan, D., & Leite, M. S. (2016). Situação epidemiológica da tuberculose no Rio Grande do Sul: uma análise com base nos dados do Sinan entre 2003 e 2012 com foco nos povos indígenas. Revista Brasileira de Epidemiologia, 19(3), 658–669. https://doi.org/10.1590/1980-5497201600030015
Mendes, A. M., Leite, M. S., Langdon, E. J., & Grisotti, M. (2018). O desafio da atenção primária na saúde indígena no Brasil. Revista Panamericana de Salud Pública, 42. https://doi.org/10.26633/rpsp.2018.184
Monteiro, C. A. (2003). A dimensão da pobreza, da desnutrição e da fome no Brasil. Estudos Avançados, 17(48), 7–20. https://doi.org/10.1590/s0103-40142003000200002
Olczak-Pruc, M., Szarpak, L., Navolokina, A., Chmielewski, J., Panasiuk, L., Juárez-Vela, R., Pruc, M., Swieczkowski, D., Majer, R., Rafique, Z., & Peacock, F. W. (2022). The effect of zinc supplementation on the course of COVID-19 – A systematic review and meta-analysis. Annals of Agricultural and Environmental Medicine: AAEM, 29(4), 568–574. https://doi.org/10.26444/aaem/155846
Rahman, M. T., & Karim, M. M. (2017). Metallothionein: a Potential Link in the Regulation of Zinc in Nutritional Immunity. Biological Trace Element Research, 182(1), 1–13. https://doi.org/10.1007/s12011-017-1061-8
Romy, K. W., Stadtmüller, M., Traikov, S., Georgi, M., Teichert, M., Yosef, H. K., Wallenborn, J., Karl, A., Schütze, K., Wagner, M., El‐Armouche, A., & Tonn, T. (2022). SARS-CoV-2 Infects Red Blood Cell Progenitors and Dysregulates Hemoglobin and Iron Metabolism. Stem Cell Reviews and Reports, 18(5), 1809–1821. https://doi.org/10.1007/s12015-021-10322-8
Sichieri, R., Coitinho, D. C., Monteiro, J. B., & Coutinho, W. F. (2000). Recomendações de alimentação e nutrição saudável para a população brasileira. Arquivos Brasileiros de Endocrinologia & Metabologia, 44(3), 227–232. https://doi.org/10.1590/s0004-27302000000300007
Sethuram, R., Bai, D., & Abu-Soud, H. M. (2021). Potential Role of Zinc in the COVID-19 Disease Process and its Probable Impact on Reproduction. Reproductive Sciences. https://doi.org/10.1007/s43032-020-00400-6
Sheftel, A. D., Mason, A. B., & Ponka, P. (2012). The long history of iron in the Universe and in health and disease. Biochimica et Biophysica Acta (BBA) – General Subjects, 1820(3), 161–187. https://doi.org/10.1016/j.bbagen.2011.08.002
Taneri, P. E., Gómez-Ochoa, S. A., Llanaj, E., Raguindin, P. F., Rojas, L. Z., Roa-Díaz, Z. M., Salvador, D., Groothof, D., Minder, B., Kopp-Heim, D., Hautz, W. E., Eisenga, M. F., Franco, O. H., Glisic, M., & Muka, T. (2020). Anemia and iron metabolism in COVID-19: a systematic review and meta-analysis. European Journal of Epidemiology, 35(8), 763–773. https://doi.org/10.1007/s10654-020-00678-5
Zapatera, B., Prados, A., Gómez-Martínez, S., & Marcos, A. (2015). Immunonutrition: methodology and applications. Nutricion Hospitalaria, 31 Suppl 3, 145–154. https://doi.org/10.3305/nh.2015.31.sup3.8762
Zemb, P., Bergman, P., Camargo Jr, C. A., Cavalier, E., Cormier, C., Courbebaisse, M., Hollis, B., Joulia, F., Minisola, S., Pilz, S., Pludowski, P., Schmitt, F., Zdrenghea, M., Souberbielle, J. C. (2020). Vitamin D deficiency and the COVID-19 pandemic. J Glob Antimicrob Resist, 22, 133-134. doi: https://doi.org/10.1016/j.jgar.2020.05.006
Zhang, Y., Yang, K., Hou, S., Zhong, T., & Crush, J. (2021). Factors determining household-level food insecurity during COVID-19 epidemic: a case of Wuhan, China. Food & Nutrition Research. https://doi.org/10.29219/fnr.v65.5501
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