Polymers of fructose: importance for the nutrition and human health
DOI:
https://doi.org/10.18593/eba.27168Keywords:
Soluble fiber, Prebiotic, Polymers of fructose, Health and well-beingAbstract
Inulin-type fructans are soluble nondigestible carbohydrates based on fructose found in many plants used in human nutrition. These polymers constituted by β-glycosidic bonds have prebiotic activity by selectively stimulating the multiplication and activity of beneficial intestinal bacteria. These microorganisms, as well as their metabolites resulting from the fermentation of fructans, have been associated to several positive effects on health and well-being such as intestinal function, immune response, metabolism, bone development, cognition and emotion in addition to preventing or improving many pathological conditions. Thus, this review aimed at raise the evidence on the effects of fructan supplementation on different aspects of human health. Therefore, it was surveyed randomized, double-blind, placebo-controlled clinical trials, published between 1995 and 2020 indexed in the databases Pubmed, Web of Science, Scielo, Scopus and Lilacs. Several studies demonstrated the benefits of fructans on many aspects of health and well-being, however, more clinical studies are necessary in order to improve the knowledge acquired until now and to fill gaps that still exist in available literature. This knowledge is essential to determine indications and possible contraindications in future therapeutic protocols.
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